Reboxetine induced erectile dysfunction and spontaneous ejaculation during defecation and micturition
by
Sivrioglu EY, Topaloglu VC, Sarandol A, Akkaya C, Eker SS, Kirli S.
Uludag University Faculty of Medicine,
Department of Psychiatry, Bursa, Turkey;
Uludag Universitesi Tip Fakultesi,
Psikiyatri Anabilim Dali,
16059 Gorukle, Bursa, Turkey.
Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):548-50


ABSTRACT

This is a case report of reboxetine induced erectile dysfunction, seminal emission and ejaculation during defecation and micturition. A 44 year old male who had been suffering from depression without any sexual dysfunction was put on venlafaxine XR treatment. Due to delayed ejaculation and occasional episodes of absence of ejaculation he was switched to reboxetine. At the second week of treatment he reported erectile dysfunction and premature ejaculation, and seminal emission and ejaculation during defecation and micturition occurred later at 8th week of treatment. After he was switched to sertraline 50 mg/day, his erectile dysfunction, premature and spontaneous ejaculation symptoms subsided in 2 weeks. Although reboxetine is reported to be free of sexual side effects, individual vulnerabilities to such unwanted effects should be considered, and sexual dysfunction should be assessed thoroughly during the treatment.


Efficacy
Selectivity
Reboxetine
Venlafaxine
NARIs and SSRIs
Sexual side-effects
Noradrenaline and mood
Catecholamine depletion
Selectivity or multiplicity?
Reboxetine and the elderly
Noradrenaline reuptake inhibition
Sexual function: paroxeine v reboxetine




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